The goal of our group is to acquire a functional understanding of the deregulation of signalling networks in disease and to apply this knowledge to novel therapeutics. This deregulation in how cell process and react to extracellular information is a hallmark of multiple pathological conditions. Our main application is cancer, but we also work on metabolic and auto-immune diseases. Logic modelling based on phosphoproteomic data is a major tool in our group towards this end.
Website: http://www.saezlab.org
Members involved in CoLoMoTo activities:- Julio Saez Rodriguez
- Attila Gabor
- Federica Eduati
- Enio Gjerga
- Melanie Rinas